The best selling album in 2000 in Portugal was SUPERNATURAL by SANTANA.
| Rank | Artist | Album | Released |
| 1 | SANTANA | SUPERNATURAL | 1999 |
| 2 | SILENCE 4 | ONLY PAIN IS REAL | 2000 |
| 3 | CARIBE SERIES | CARIBE MIX 2000 | 2000 |
| 4 | BRITNEY SPEARS | OOPS!...I DID IT AGAIN | 2000 |
| 5 | ENRIQUE IGLESIAS | ENRIQUE | 1999 |
| 6 | THE CORRS | IN BLUE | 2000 |
| 7 | ALANIS MORISSETTE | MTV UNPLUGGED | 1999 |
| 8 | SOUNDTRACK | TERRA NOSTRA | 2000 |
| 9 | LENNY KRAVITZ | GREATEST HITS | 2000 |
| 10 | THE BEATLES | 1 | 2000 |
Source: AFP