The best selling music DVD video in 2010 in Italy was THIS IS IT by MICHAEL JACKSON.
| Rank | Artist | Video | Released |
| 1 | MICHAEL JACKSON | THIS IS IT | 2010 |
| 2 | VARIOUS ARTISTS | AMICHE PER L'ABRUZZO | 2010 |
| 3 | U2 | U2 360º AT THE ROSE BOWL | 2010 |
| 4 | MICHAEL JACKSON | LIVE IN BUCHAREST - THE DANGEROUS TOUR | 2005 |
| 5 | BRUCE SPRINGSTEEN | LONDON CALLING LIVE IN HYDE PARK | 2010 |
| 6 | MICHAEL JACKSON | MICHAEL JACKSON'S VISION | 2010 |
| 7 | PINK FLOYD | LIVE AT POMPEII | 1989 |
| 8 | TIZIANO FERRO | ALLA MIA ETÀ LIVE IN ROME | 2009 |
| 9 | TOKIO HOTEL | HUMANOID CITY LIVE | 2010 |
| 10 | PINK FLOYD | P.U.L.S.E. | 1995 |
| 11 | VARIOUS ARTISTS | IL MONDO DI PATTY...LA STORIA PIU BELLA A TEATRO | 2010 |
| 12 | MICHAEL JACKSON | NUMBER ONES | 2003 |
| 13 | POOH | ANCORA UNA NOTTE INSIEME | 2010 |
| 14 | RENATO ZERO | ZERONOVETOUR PRESENTE | 2010 |
| 15 | CLAUDIO BAGLIONI | Q.P.G.A. FILMOPERA | 2010 |
| 16 | FABRIZIO DE ANDRE | DE ANDRE' IN CONCERTO | 2004 |
| 17 | GEORGE MICHAEL | LIVE IN LONDON | 2009 |
| 18 | VASCO ROSSI | IL MONDO CHE VORREI LIVE | 2008 |
| 19 | MARIO BIONDI | I LOVE YOU MORE | 2009 |
| 20 | IRON MAIDEN | FLIGHT 666 | 2009 |
Source: FIMI