The best selling album in 2021 in Czech Republic was NOČNÍ OBRAZ by VLADIMÍR MIŠÍK.
| Rank | Artist | Album | Released |
| 1 | VLADIMÍR MIŠÍK | NOČNÍ OBRAZ | 2021 |
| 2 | ABBA | THE ALBUMS 9CD BOX | 2008 |
| 3 | ABBA | VOYAGE | 2021 |
| 4 | YZOMANDIAS | PROZYUM | 2021 |
| 5 | VIKTOR SHEEN | BARVY | 2021 |
| 6 | IRON MAIDEN | SENJUTSU | 2021 |
| 7 | KAREL GOTT | 80/80 NEJVĚTŠÍ HITY 1964-2019 | 2019 |
| 8 | KRYŠTOF | HALYWŮD | 2021 |
| 9 | DUA LIPA | FUTURE NOSTALGIA | 2020 |
| 10 | POKÁČ | ANTARKTIDA | 2021 |
Source: ČNS IFPI