The best selling album in 2010 in Argentina was EN TOTAL PLENITUD by MARCO ANTONIO SOLIS.
| Rank | Artist | Album | Released |
| 1 | MARCO ANTONIO SOLIS | EN TOTAL PLENITUD | 2010 |
| 2 | RICARDO ARJONA | POQUITA ROPA | 2010 |
| 3 | SANDRO | SANDRO LO MEJOR ( CD+DVD) | 2007 |
| 4 | TEENANGELS | TEENANGELS 4 | 2010 |
| 5 | CHAYANNE | NO HAY IMPOSIBLES | 2010 |
| 6 | LUIS MIGUEL | LUIS MIGUEL | 2010 |
| 7 | RICARDO MONTANER | SOY FELIZ | 2010 |
| 8 | JOAN MANUEL SERRAT | HIJO DE LA LUZ Y DE LA SOMBRA | 2010 |
| 9 | JUSTIN BIEBER | MY WORLD 2.0 / MY WORLDS | 2010 |
| 10 | MADONNA | STICKY & SWEET TOUR | 2010 |
Source: CAPIF